![]() ![]() Recently, some cases of somnambulism or sleep‐related eating disorder (SRED) have been reported in patients treated with these drugs. This study investigated the risk of reporting somnambulism or SRED associated with the use of antipsychotics and lithium. ![]() Methods: The World Health Organization pharmacovigilance database (VigiBase), comprising >18 million adverse events, was queried. All somnambulism or SRED reports related to antipsychotics or lithium were identified. The association between antipsychotics or lithium and somnambulism or SRED was computed using the proportional reporting ratio (PRR) and information component. Results: Among the 5784 cases reporting somnambulism or SRED, 508 suspected at least 1 antipsychotic or lithium. ![]() ![]() Most patients were aged 18–64 years (62.0%), and 37.0% were men. In most cases (77.6%), antipsychotic or lithium were the only drug class involved, and 53.3% of cases suspected quetiapine. Somnambulism was reported in 88.6% of cases and SRED in 18.1%. Conclusions: We found a significant signal of somnambulism or SRED related to second‐generation antipsychotics and lithium.Ī significant association was found for second‐generation antipsychotics (PRR 3.44, 95% confidence interval 3.13) and lithium (PRR 2.03, ), but not for first‐generation antipsychotics (PRR 0.99, ). While case reports mentioned mostly quetiapine and olanzapine, almost all second‐generation antipsychotics were associated with somnambulism or SRED.Nearly all industries have had to adapt amid the COVID-19 pandemic. Not all sectors have had the same experience in adjusting to prevent spreading the virus, though. Heavy industries like construction and manufacturing face a unique challenge concerning new safety precautions.Īt the peak of COVID-19 regulations, 42% of the workforce was working from home. That’s a luxury most construction and manufacturing workers don’t have, given the hands-on nature of their work. News of COVID-19 outbreaks at construction sites highlight how difficult it can be to make these workspaces safe.ĭespite these challenges, some heavy industry companies have managed to adapt to COVID-19 precautions. While not all construction and manufacturing workers can go remote, some can. Office workers can perform most, if not all, of their duties from home, and they should if feasible. Moving these employees away from a facility minimizes the number of people in the building and prevents any cross-department virus transmission.Įmployees who have to work on-site can still go remote in some situations. The Centers for Disease Control and Prevention (CDC) recommends that construction companies cancel or postpone in-person meetings, but another solution is to hold these events virtually. Instead of speaking to employees at the worksite, managers can use video conferencing services for trainings, safety briefings or other meetings. Some managers may be able to use drones or cameras to oversee operations without being physically present. Reorganizing Workspaces to Minimize Contact Similarly, these technologies can give investors or clients remote access to their projects. ![]()
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